The use of Botox, also know as botulinum toxin, is by far and away the most popular noninvasive procedure to help curtail the signs of aging. In this study from Science Daily, the effects of this neuromodulator are updated:

‘Advances and Refinements’ in Neuromodulators for Facial Rejuvenation — ScienceDailyBeautiful Woman

Use of neuromodulators for minimally invasive facial rejuvenation has grown rapidly in recent years — by approximately 750 percent from 2000 to 2014, according to ASPS statistics. Cosmetic injection of onabotulinum toxin A — best known by the brand name Botox — is by far the most common plastic surgery procedure, with more than 6.5 million procedures performed in 2015.

Other currently approved FDA-approved products include abobotulinum toxin A (Dysport) and incobotulinum toxin A (Xeomin). While all of these products have “equivalent success in appropriately trained hands,” the researchers note that they are not interchangeable in terms of dosage and effects. All three products are specifically approved for treatment of “frown lines” and “crow’s feet”; plastic surgeons may use them “off-label” to treat other types of facial wrinkles as well.

Dr. Rohrich has demonstrated his step-by-step approach to facial rejuvenation with Botox. The technique begins with comprehensive analysis of the patient’s facial appearance, including the effects of facial movement and any asymmetrical areas. The plastic surgeon must have an intimate understanding of the facial muscles — how they contribute to “dynamic” facial wrinkles and the proper neurotoxin dose and injection technique to produce the desired effect.

Read the full article here:  ‘Advances and Refinements’ in Neuromodulators for Facial Rejuvenation — ScienceDaily

In this video, the professor of plastic surgery at Emory University in Atlanta, Georgia discusses the advances in using Botox as a neuromodulator for more than just reversing the signs of aging. He feels there is potential to help improve the quality of life for those experiencing depression, especially from debilitating diseases such as Alzheimers.

There are other neuromodulators besides Botox, and even though they are similar in the fact that they all temporarily block nerve activity in muscles, but each diffuses differently. This makes the placement of the injection very critical to having the proper results. The most popular types are Botox, Dysport, and Xeomin – which one is for you?:

Botox, Dysport, Xeomin differences explained by experts | Dermatology TimesPlastic Surgery

Botox (onabotulinumtoxinA, Allergan) first earned Food and Drug Administration (FDA) approval in 1989. Dysport (abobotulinumtoxinA, Medicis) was approved in 2009. Xeomin (incobotulinumtoxinA, Merz) was FDA-approved in July 2010 for treatment of adults with cervical dystonia or blepharospasm.

Dr. Smith Among FDA-approved products, “There’s no easy way to convert patients from one to the other. You can’t just multiply the Botox dosage by 2.5, put patients on Dysport and hope for the best,” says Kevin C. Smith, M.D., an Ontario-based dermatologist in private practice. “It’s not just a matter of the dose.” Because these products diffuse differently, achieving comparable results when switching from one drug to the other may require alteration in injection points, he explains.

If converting from Botox to Dysport to treat glabellar frown lines, Dr. Smith says physicians might want to inject higher above the eyebrow. If the physician injects 2.5 units of Dysport in the same spot where one would inject Botox, he explains, “Because Dysport spreads a little more, there’s a chance that it will diffuse downward into the upper eyelid, causing it to droop. You might also have to adjust the dose up or down. If you mechanically give everyone 2.5 times the Botox dose, you’ll be high in some cases and low in others. It’s like working with a different material entirely.”

Read the full post here:  Botox, Dysport, Xeomin differences explained by experts | Dermatology Times

The thing you have to remember with any of the above-mentioned injections, none of them are permanent and you will need to be retreated within 3 to 6 months. Finding a cosmetic surgeon that you can trust to give you the best advice is essential. They would be able to explain the differences and guide you toward making the correct choice.